R&D Models: Lessons from Vaccine History

A preventive HIV vaccine offers the best hope for ending the AIDS pandemic. Scientific evidence suggests that an HIV vaccine is possible, and funding for HIV vaccine research and development (R&D) has increased substantially in recent years. The speed of progress toward an HIV vaccine will depend on the management of the effort as well as on its scale, however, and organizational issues have been the subject of vigorous debate. With this paper, we seek to shed light on these debates by examining the history of vaccine development, as well as some examples of large R&D initiatives in other areas. We focus on two issues: the roles of the public and private sectors, and the merits and risks of strong central direction of R&D. We also consider the scientific, regulatory, and institutional changes that complicate extrapolation from past experience to the case of HIV vaccines. Our analysis draws on extensive interviews with experts in the field as well as a literature review.

Link to Full Text

Source

International AIDS Vaccine Initiative, Policy Research Working Paper #14, June 2007.

Related Content

This is a controversial and troubling question for nations and citizens (especially if they are feeling insecure). But daily reality brings more important questions than this: the need to find food, shelter, and preserve or improve one’s health. “Development” in the abstract is a little distracting if it doesn’t speak directly to these essential concerns. Are developed societies those with healthy citizens and residents?

Market Menagerie examines technological advance and market regulation in the health industries of nations such as India, Brazil, South Africa, Nigeria, and China. Pharmaceutical and life science industries can reinforce economic development and industry growth, but not necessarily positive health outcomes. Yet well-crafted industrial and health policies can strengthen each other and reconcile economic and social goals.

Very little detail is known about how investments and industrial policy options exercised by the national and regional State within large economies such as Brazil and India are affecting industrial employment and regional socio-economic development. The TCLab “Employment and Regional Inequality (TERI)” project is a comparative analysis of technological and industrial policy choices and their impact on intersectoral and regional employment inequalities observed both in India and Brazil.

"The gains from the technology and industry perspective have already been put into motion,"  Smita Srinivas interviewed by Ozy.com for USA Today

India has launched the country's first-ever Mars Orbiter Mission (MOM) and is expected to reach Mars in September.

Melissa Pandika, OZY.com 10:54 a.m. EST January 29, 2014

(Photo Credits: Pallava Bagla/Corbis)